Glyphosate, the active ingredient in Roundup herbicide, has been making headlines for its potential to cause cancer, but another serious disease has also been linked to this ubiquitous chemical: non-alcoholic fatty liver disease (NAFLD), particularly the most advanced cases. Staggering amounts of glyphosate have been applied worldwide in recent decades. Since 1974, for instance, more than 1.6 billion kilograms (or about 3.5 billion pounds) of glyphosate have been used in the U.S. alone, accounting for 19% of its overall usage worldwide. Two-thirds of the total volume of glyphosate applied in the U.S. from 1974 to 2014 was applied in the last 10 years1 — a time during which rates of NAFLD also increased. As more and more glyphosate has been sprayed on agricultural lands, parks, and backyards, entering our food and water supplies, NAFLD rates have trended upward, from a prevalence of 15% in 2005 to 25% in 2010.2 Is there a connection? The answer increasingly appears to be yes.